Extrusion and pelletizing in the pharmaceutical industries
The PFS product line includes newly developed machines for the manufacture of pellets for pharmaceutical products and drugs, as well as additives, all from a single source. MAAG offers innovative solutions, especially in micropelletizing, for a wide range of applications in the pharmaceutical industry. MAAG’s micropelletizing technologies produce particles of uniform shape and size for optimal and direct further processing.
Tablets and capsules are currently the most popular oral solid dosage form in the pharmaceutical industry. Pellets are not powder and not granulate; they are characterized by a defined shape and a very narrow particle size distribution. This allows a very wide range of applications of pellets that integrate active substances. Employing hot melt/melt extrusion, even the processing of poorly soluble carrier/active substance combinations, no longer poses a major problem in the pharmaceutical industry. Continuous manufacturing delivers many benefits in production and in speeding up the development cycles for new drugs.
Most relevant products for this application
extrex® PFS - 20GP
The extrex® PFS gear pumps are specially designed for applications in the pharmaceutical industries. Such applications require specific design characteristics: high discharge pressure capability, constant throughput, gentle conveying, and narrow temperature ranges. In such an environment, the proven extrex® gear pumps unfold their full potential. [...]
Belt-Cooling Pelletizing System PFS Series 30
The Belt-Cooling Pelletizing System PFS is specially designed for water soluble and brittle formulations. The variable system configuration enables perfect adaptation to the product being processed and guarantees continuous manufacturing. Even elastic and very flexible polymers can be handled by the belt system in a simple and efficient way. The system produces top-quality cylindrical pellets… [...]
The drop pelletizing system DROPPO® PFS is suited to processing low-viscosity melts and fluids with viscosity less than 500mPas. The system can be used in many ways; for example, for fatty acids, organic waxes, polyalcohols, or saccharides. Another application is the production of active ingredients for the flavor and food industry; for instance, encapsulation. The… [...]
The widely tried and proven dry-cut strand pelletizer produces top quality cylindrical or micro-pellets, which are ideal for further downstream processing. Its compact design makes the strand pelletizer very suitable for lab applications. The variable system configuration enables a perfect adaptation to the product being processed with high flexibility when changing products [...]
Strand Cooling Belt PFS
Unlike conventional extrusion in a water bath, the Strand Cooling Belt PFS does not require manual threading of strands. Strands are deposited directly on the conveyor belt and automatically conveyed to the strand pelletizer. The cooling is done by special air nozzles with high cooling capacity. [...]
The pelletizing system, thanks to its enclosed design, is ideal for pelletizing carrier/agent combinations in hot-melt extrusion processes and was developed specifically for the manufacture of pharmaceutical products. [...]