SPHERO® PFS
The pelletizing system, thanks to its enclosed design, is ideal for pelletizing carrier/agent combinations in hot-melt extrusion processes and was developed specifically for the manufacture of pharmaceutical products.
Technical Data SPHERO® PFS 70
| Pump | extrex® 20 to 36 GP |
|---|---|
| Differential pressure Δp | max. 250 bar |
| Temparature range | 30°C – 200°C |
| No. of holes | 1-12 |
| Throughput | 0,3 – 20 kg/h |
| Pellet size | 0,5 – 5 mm |
Application Areas
- Pelletizing of water-soluble carrier/active ingredient combination
- Micro-pellets for tamper-resistant and abuse-deterrent formulation
- Production of MUPS (Multiple Unit Pellet System) tablets
- Continuous operation or batch production
- Highly potent active pharmaceutical ingredients
- For pelletizing from an extruder or reactor vessel
Advantages
- Enclosed system (containment)
- Narrow distribution of particle size
- Homogeneous pellet shape featuring great flow-ability
- Quick and easy to clean
- Low-dust pelletizing
- Pelletizing of brittle formulations
- Special design for pelletizing sticky products
- Simplified, speeded up development of innovative pharmaceutical formulation